Lab Testing

The Array 11 Chemical Immune Reactivity Screen is an invaluable tool recommended for patients exhibiting various immune-related conditions. It aids in identifying the loss of immune tolerance triggered by xenobiotic exposure, potentially leading to autoimmune reactivity. This test offers insights into autoimmune diseases and related family histories by assessing chemical sensitivities, intolerance, and abnormal immune function. Moreover, it assists in formulating guidelines for avoiding specific chemicals to mitigate the risk of autoimmune processes, making it indispensable for comprehensive patient care.

The Array 10-90 panel evaluates immune reactions to 90 of the most commonly consumed raw and/or modified foods, food enzymes, lectins, and artificial food additives tested as part of the Array 10 panel. It can detect dietary-related triggers of autoimmune reactivity and monitor the efficacy of customized dietary protocols.

The Chemical Immune Reactivity Screen, also known as Array 11, goes beyond conventional tests by measuring the immune response to chemicals bound to human proteins rather than merely identifying chemical exposure levels. This unique approach provides valuable insights into an individual's health risk from chemical exposure and its impact on the body. Array 11 assesses a comprehensive range of chemical toxins that can bind to body tissues due to environmental exposure, offering a detailed analysis of the antigens tested. It is particularly beneficial for patients experiencing increased chemical sensitivity or intolerance, abnormal immune system functioning, autoimmune conditions, or with a family history of autoimmune disease. Clinically, Array 11 helps identify the loss of immune tolerance associated with chemical exposure, guides the avoidance of specific chemicals to mitigate autoimmune reactivity, and monitors the effectiveness of clinical management for patients.

The human body is home to a vast variety of microorganisms that help keep you healthy, so long as it is well balanced. In your gut alone, there are thought to be at least ten times more microbes than there are human cells in your whole body. These micro-organisms regulate many important bodily functions aid your immune system in developing and maturing in infancy and childhood, and help keep you healthy throughout your lifetime. The human microbiota is influenced by many factors, including genetic makeup, diet, environmental exposures, stress, sleep, and activity. However, new industries, new chemicals and drugs, and new foods can overload your immune system, effectively overwhelming your body with more and more environmental stressors. This can lead to your microbiome becoming imbalanced, which can open the floodgates to invading pathogens, acute infections, as well as colonization by non-beneficial bacteria, viruses, yeasts, and parasites. As your immune system attempts to restore balance, it can end up "attacking" your own cells, tissues, and/or organs that have been infected or contaminated with infectious agents. This may or may not eventually result in autoimmune reactivity. Array 12 assesses a variety of infectious agents as triggers of autoimmunity: those that are found in the body as well as those that we may be exposed to in our environment. These include oral pathogens, gastrointestinal pathogens, gut parasites, bacterial and stealth pathogens, environmental molds, viral pathogens, and tick-borne pathogens, including Borrelia burgdoferi, which is known to cause Lyme disease.

Many studies show that the autoimmune antibody can be elevated in the blood many years before symptoms occur. Cyrex Labs has now developed its Cyrex Labs Array #5, a comprehensive autoimmune screen that helps in the early detection of autoimmunity. If detected early, natural and/or medical interventions can begin in order to minimize long-term illness and promote a better quality of life. Multiple autoimmune antibodies are tested in this panel due to the fact that more than 40% of those with autoantibodies in one area have autoantibodies in other areas of the body. The Cyrex Array #5 tests the gamut of autoimmune antibodies in order to minimize "missing" a potential autoimmune condition.

Vibrant America provides a health analytics tool designed to detect genetic polymorphisms linked to various cardiovascular conditions such as heart disease, hypertension, diabetes, insulin resistance, atrial fibrillation, stroke, and dyslipidemia. Heart disease encompasses a wide range of conditions affecting the heart, including infections, genetic defects, and blood vessel diseases. While many forms of heart disease are preventable through healthy lifestyle choices, it remains the primary health concern globally. Given its prevalence and severity, understanding one's cardiovascular risk factors is crucial. Vibrant America offers a comprehensive range of tests aimed at assessing individual risk profiles or monitoring existing conditions. Heart disease stands as the leading cause of death worldwide, affecting both men and women. Surprisingly, women are just as susceptible to heart attacks as men, and in some cases, even more so. Despite this, more women than men succumb to heart disease annually, and women also face a higher risk of mortality following their first heart attack.

The Cleveland Heart Lab Inflammation Profile PLUS 4 offers advanced testing beyond routine lipid screening, aiming to assess cardiovascular risk comprehensively. While traditional cholesterol testing is crucial, it may not present the complete cardiovascular health picture. Recent evidence suggests inflammation within the artery wall significantly contributes to heart attacks and strokes, even in individuals with normal cholesterol levels. This test evaluates inflammatory status using blood and urine biomarkers, providing insights into a patient's cardiovascular risk spectrum. By monitoring inflammation levels, healthcare providers can detect and treat inflammation early, potentially reducing the risk of cardiovascular events over a patient's lifetime. This comprehensive test encompasses biomarkers related to lifestyle concerns, metabolic diseases, and cardiovascular risk, including F2-IsoPs, OxLDL, ADMA/SDMA, Microalbumin, hsCRP, Lp-PLA2 Activity, MPO, TMAO, CoQ10, OmegaCheck, and the Insulin Resistance Panel and Score, which aids in diagnosing glycemic disorders and assessing insulin resistance, offering valuable information for managing diabetes and related conditions.

Cyrex Array 2 is a comprehensive antibody assessment that evaluates the integrity of the intestinal barrier and the presence of bacterial endotoxins, such as lipopolysaccharides. It examines key markers, including tight-junction proteins like occludin and zonulin, as well as cell cytoskeleton proteins like actomyosin. By identifying both transcellular and paracellular routes of intestinal barrier penetration, this test offers insights into "leaky gut" - the passage of large molecules between intestinal cells. This information helps assess the potential challenges to the immune system and guides strategies for gut health optimization.

The Cyrex Array 22 lab test is designed to identify factors contributing to intestinal dysbiosis and impaired gut barrier function. By evaluating markers associated with bacterial overgrowth in the small intestine and the release of bacterial cytotoxins, this test helps assess the integrity of the intestinal barrier and the risk of autoimmune activation. Specifically, it aids in guiding treatment protocols for conditions like irritable bowel syndrome (IBS) and small intestinal bacterial overgrowth (SIBO), offering valuable insights for individuals experiencing symptoms such as malabsorption, weight loss, anemia, fatty stools, fatigue, reflux, skin disorders, obesity, or food intolerances. Given that a significant portion of IBS cases stem from bacterial infections producing cytolethal-distending toxins, the Cyrex Array 22 test provides crucial information on immune dysregulation, low-grade inflammation, and altered gastrointestinal permeability, facilitating accurate diagnosis and tailored treatment plans.

The DUTCH Plus™ test represents an advanced approach to hormone testing, offering a comprehensive analysis of sex hormones, their metabolites, and the diurnal pattern of free cortisol. It provides insight into the total and distribution of cortisol metabolites while also incorporating the Cortisol Awakening Response (CAR) to shed light on the hypothalamic–pituitary–adrenal (HPA) axis. With analysis of 35 different hormones, including estrogen, progesterone, testosterone, DHEA-S, and cortisol, alongside their metabolites, the DUTCH Plus™ offers a comprehensive overview of hormonal balance. Additionally, it includes DUTCH Extras such as Melatonin (6OHMS) and 8-Hydroxy-2-deoxyguanosine (8-OHdG) for a more thorough assessment of adrenal function and overall hormone health.

The GI Map utilizes cutting-edge DNA Multiplex technology to comprehensively assess your microbiome using just a single stool sample. This advanced panel focuses on identifying microbes that could disrupt the normal balance of gut flora, potentially leading to gastrointestinal disturbances or illness. It covers a wide range of microbial targets, including pathogenic bacteria, commensal bacteria, opportunistic pathogens, fungi, viruses, parasites, and immune and digestive markers. You will receive a specimen collection kit for convenient at-home sampling.

Genomic Spotlight leverages advanced machine learning through the Opus23 informatics platform to provide clinicians with unparalleled insights into a patient's genomics. With a simple buccal collection, this comprehensive DNA test reports clinically significant single nucleotide polymorphisms (SNPs) across multiple domains, evaluating eight crucial areas of health, including methylation, structural health, cognitive function, detoxification, endocrine balance, inflammation, and gastrointestinal wellness.

GI Spotlight functional wellness test offers a comprehensive analysis of your gut microbiome's health, utilizing cutting-edge quantitative polymerase chain reaction (qPCR) technology. This test provides insight into key areas such as Keystone microbial diversity, gut fungal balance, intestinal permeability, gut barrier function, digestive function, nutrient absorption, GI motility, inflammatory status, and immune function in the gut.

Introducing IBSSmart: A Revolutionary Blood Test for Diagnosing IBS. This groundbreaking test measures the levels of two validated IBS biomarkers, anti-CdtB and anti-vinculin, providing a simple yet highly effective means of diagnosing IBS. Elevated levels of these biomarkers are commonly found in IBS patients experiencing diarrheal symptoms, allowing for the diagnosis of diarrhea-predominant or mixed-type IBS (IBS-D or IBS-M). Notably, these biomarkers are not typically elevated in patients with constipation-predominant IBS (IBS-C). The validation study for IBSSmart demonstrates that elevated biomarkers indicate IBS with up to 100% positive predictive value, making it an incredibly reliable diagnostic tool. Moreover, IBSSmart offers high specificity in distinguishing between IBS and IBD, providing clarity and accuracy in diagnosis.

The Immunoscience Autoimmune Comprehensive Panel is a comprehensive test designed to detect approximately 100 autoimmune disorders, addressing both preclinical and clinical stages of autoimmune diseases, which affect 5-9% of the population. This panel is particularly valuable as it can identify pathogenic autoreactive antibodies or reactive T cells against specific self-antigens in the blood, often years before the onset of active disease. Research has shown that these autoantibodies may be present in the blood for several months to nearly two decades before the manifestation of various autoimmune conditions. The panel includes a range of markers such as ANA, ENA, RF, dsDNA, Actin, Mitochondrial Antibodies, and Total C1Q Immune Complexes, offering insights into autoimmune conditions affecting different systems. It is especially beneficial for individuals with elevated antibodies against various viruses, including EBV, CMV, Herpes 1+2, HHV-6, VZV, and Measles, aiding in early detection and intervention for improved patient outcomes.

The hsLRA™ tests stand out as the most comprehensive and specific assessments compared to other laboratory tests, offering valuable insights into the hidden causes of many common health concerns. These revolutionary blood tests directly analyze lymphocytes, the body's long-lived, memory-carrying white blood cells crucial for indicating overall health and detecting disease. What sets LRA tests apart is their unique ability to simultaneously measure all three types of delayed sensitivity reactions: lymphocyte activation, reactive antibody responses (including IgA, IgM, and IgG), immune complexes, and T cell direct activation. This comprehensive approach provides healthcare providers with a thorough understanding of immune system reactivity and aids in crafting tailored treatment strategies for patients.

The Metabolomics Spotlight functional wellness test offers a comprehensive examination of an individual's biochemistry and metabolism, aiding practitioners in understanding metabolic pathways and assessing metabolic status. This detailed report delves into critical areas such as metabolic processing, mitochondrial function, amino acid metabolism, inflammatory response, detoxification, stress, and mood, providing valuable insights into overall well-being.

The Organic Acids Test (OAT) provides a comprehensive assessment of overall health with over 70 markers, including intestinal yeast and bacteria levels. Elevated levels of these microorganisms can contribute to various health issues, such as behavior disorders, hyperactivity, fatigue, and immune dysfunction. Factors like antibiotic use, high sugar diets, and genetic predispositions can lead to abnormal organic acid levels. Additionally, our test evaluates vitamin, mineral, and neurotransmitter levels and oxidative stress, offering valuable insights into chronic illnesses. Moreover, it uniquely includes markers for oxalates, which are closely linked to many health conditions.

The Comprehensive Metabolic Panel (CMP) is made up of 14 tests that provide comprehensive insights into a person's metabolic status, assessing the functionality of vital organs such as the kidneys and liver, electrolyte balance, acid/base equilibrium, and blood glucose and protein levels. The CMP includes examinations for Albumin, Albumin/Globulin Ratio, Alkaline Phosphatase, ALT, AST, BUN/Creatinine Ratio, Calcium, Carbon Dioxide, Chloride, Creatinine with GFR Estimated, Globulin, Glucose, Potassium, Sodium, Total Bilirubin, Total Protein, and Urea Nitrogen, as well as Platelet Count. Additionally, it incorporates other assessments such as the FIB 4 Index for liver inflammation, NASH, and liver fibrosis, a CBC with differential for a comprehensive analysis of white and red blood cells, and an Inflammation Panel evaluating markers like ADMA/SDMA, F2-Isoprostane/Creatine, hs-CRP, Lp-PLA2, Myeloperoxidase, OxLDL, and TMAO. Lipoprotein Fractionation is included to analyze various lipoprotein particles, while the Insulin Resistance section measures insulin and C-peptide levels to determine insulin resistance. The panel also includes assessments for APOE4 genotype and a Thyroid Complete with antibodies, encompassing TSH, Total T4, Total T3, TPO, and TAA markers, offering a comprehensive overview of metabolic health and potential risk factors.

A breath test can help you determine if your symptoms are caused by treatable conditions like small intestinal bacterial overgrowth (SIBO). Breath testing is a way for healthcare providers to identify specific conditions related to the gut microbiome by analyzing fermented gases found in a patient’s exhaled breath. Three fermented gases are detectable with breath testing: hydrogen, methane, and newly measurable hydrogen sulfide. While healthy levels of hydrogen, methane, and hydrogen sulfide can be present in the gut microbiome, abnormal levels can indicate a disorder and provide valuable insight into the proper treatment.

The Immunoseroogy of Lyme Panel A/B offers a comprehensive testing approach for the detection of active and chronic Lyme disease, which can lead to serious conditions such as Lyme arthritis and neuroborreliosis. This panel assesses antibodies against the spirochete and various components of B. Burgdorferi, its subspecies, and co-infections. Utilizing Borrelia antigens grown in culture and proteins expressed in vivo, this test aims to enhance accuracy. Employing patented ELISA methodology and the Western Blot method, both IgG and IgM antibodies are measured against a range of Borrelia antigens and proteins, including Outer Surface Proteins A, B, C, and E, Leukocyte Function Associated Antigen, Variable Major Protein, and more. Antibodies against Borrelia subspecies Sensu stricto, Afzelii, Garinii, Myamotoi, as well as co-infections like Babesia, Ehrlichia, and Bartonella, are also assessed separately. Early and accurate diagnosis is crucial to prevent misdiagnosis and unnecessary treatments with potential side effects. The inclusion of the Western Blot in Panel B helps mitigate the risk of false positive or negative results, ensuring appropriate management and minimizing potential long-term consequences associated with Lyme disease.

The Lymphocyte MAP™ test identifies 29 key lymphocyte biomarkers and determinants, including Th1, Th2, CD4, CD8, Treg, Th17, and the family of NK cells, the Lymphocyte MAP™ measures the integrity of the immune system at the cellular level. Additionally, the Lymphocyte MAP™ offers the most comprehensive immunophenotyping panel on the market, providing a broad picture of immune status. This comprehensive assessment allows for the identification of underlying conditions triggering various immune responses, ranging from deficiencies to over-activity, infections, inflammation, autoimmunity, allergies, asthma, hypersensitivities, and cancers. With applications ranging from healthy lifestyle optimization to the management of autoimmune conditions or recent exposure to COVID-19, the results of the Lymphocyte MAP™ can inform tailored treatment regimens, ultimately aiming to achieve "immune harmony."

The Neural Zoomer™ Plus is a sophisticated array of neurological autoantibodies designed for precise antibody-to-antigen recognition. This advanced test evaluates an individual's reactivity to 48 neurological antigens, offering insights into various neurologically related diseases. With a comprehensive panel of well-studied autoantibodies, the Neural Zoomer™ Plus empowers healthcare providers to tailor treatment protocols based on the underlying mechanisms of disease progression, thereby facilitating improved health outcomes in the complex realm of neurological disorders.

The Thyroid Complete Antibodies test is a comprehensive blood panel designed to assess thyroid function, including hypo/hyperthyroidism, secondary hypothyroidism, and autoimmune thyroiditis. This test analyzes a range of analytes and markers, including TSH, TT3, TfT4, rT3, TPO, and TAA, providing valuable insights into thyroid health and aiding in diagnosing and managing thyroid-related disorders.

The TriMercury Test is a groundbreaking clinical tool that distinguishes between methyl mercury and inorganic mercury, offering unique insights into mercury exposure and detoxification. With a simple blood draw, this test measures levels of 15 metals, including essential nutrients and potentially toxic elements, helping clinicians identify imbalances that may indicate heavy metal toxicity. By providing detailed information on the body's mercury levels and mineral ratios, this test guides personalized detoxification strategies for optimal health.

Environmental toxins, known as toxicants, encompass substances generated within the human body that, upon absorption, inhalation, or ingestion, can lead to acute or chronic toxic overload, resulting in diverse biological manifestations across organ, tissue, and cellular levels. These toxins, comprising both human-made and naturally occurring cancer-causing chemicals and endocrine disruptors, exhibit variable effects on individuals, influenced by factors such as genetics, environment, diet, liver and kidney health, microbiome composition and diversity, age, adiposity, gender, and immune system capacity. Detecting toxic overload is essential, especially in individuals presenting with chronic inflammatory symptoms, resistance to weight loss, and signs of excessive total toxic load, as it can unveil hidden chemical exposure from everyday products, foods, and surroundings. Screening for environmental toxins provides practitioners with invaluable insights into the underlying causes of toxicity, facilitating targeted detoxification strategies and promoting healing.

The Vibrant Mycotoxins test offers a comprehensive assessment of 31 common mycotoxins present in molds that humans may be exposed to, using a urine-based assay on a proprietary microarray platform. This highly accurate testing method provides valuable insights into the presence of these elusive toxins, which can lead to serious health conditions in individuals, particularly those living or working in older buildings, water-damaged environments, or with compromised immune systems and heightened oxidative stress levels. Mycotoxins pose significant health risks, potentially contributing to autoimmune diseases and cancer, making early detection and intervention crucial.

The Vibrant Gut ZoomerTM is a cutting-edge test that delves deep into the gut microbiome, analyzing microorganism 16sRNA from a stool sample to assess the relative abundance of bacteria, candida yeast, parasites, and viruses compared to a reference range. With over 1000 species of bacteria residing in the large intestine, the gut microbiome plays crucial roles in immune system modulation, nutrient metabolism, and maintaining the intestinal mucosal barrier. Imbalances in the gut microbiome can lead to various gastrointestinal symptoms, skin conditions, autoimmune disorders, and inflammatory conditions. The comprehensive report generated by the Vibrant Gut ZoomerTM provides actionable insights and recommendations tailored to the individual's specific microbial profile, including potential risks for intestinal permeability, intestinal disorders, heart health, autoimmune disorders, metabolic disorders, and nutritional deficiencies. This test offers a comprehensive analysis of the gut microbiome ecosystem, aiding in the understanding of its connection to disease and inflammation and providing personalized dietary and supplementation recommendations to support gut health and overall well-being.

The Vibrant Health Wheat Zoomer test is a comprehensive blood test designed to screen for both leaky gut and wheat sensitivity, offering precise identification of affected individuals. With the increasing recognition of gluten and wheat sensitivity in the medical community, there is a growing demand for accurate and highly sensitive testing methods. The Wheat ZoomerTM addresses this need by specifically detecting antibodies to wheat peptides, including gluten and non-gluten components, as well as antibodies indicating the presence of leaky gut. Additionally, it utilizes a highly sensitive peptide-based array to detect autoimmune reactions to gluten, providing detailed insights into a patient's immune response to wheat. For specific details, please refer to the attached documents.